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Treatment

Treatment of cervical cancer will depend on a number of factors, including:

  • The stage of the cancer
  • The size of the tumor
  • The patient's desire to have children
  • The patient's age and overall health

Treating cervical cancer when a woman is pregnant depends on two factors: the stage of pregnancy and the stage of cervical cancer. Treatment may be delayed until the baby is born if a woman is in her third trimester of pregnancy. Treatment may also be delayed in pregnant women if cervical cancer is detected before it has spread.

Surgery

Small Precancerous Lesions:
The following surgical procedures may be used for precancerous lesions or for cancerous tissue that has not spread beyond the cervix.

Cryosurgery (cryotherapy): This surgical procedure uses an instrument to freeze and destroy precancerous tissue.

Laser surgery: This surgical procedure uses a narrow laser beam to destroy precancer cells. This is not used on invasive cancer. A benefit of laser treatment is its precision; it destroys only diseased tissue inside in the cervix.

LEEP (loop electrosurgical excision procedure): This procedure uses electrical current passed through a thin wire hook. This is primarily used on precancerous lesions under local anesthesia. The advantage of this procedure is that more of the tissue can be removed for evaluation.

Cone: A gynecologist uses the same procedure as a cone biopsy to remove all of the cancerous tissue. This procedure can be used in a woman who has a very small cancerous area and who wishes to preserve the ability to have children

Hysterectomy: This surgery removes the uterus and the cervix. This kind of procedure is performed only on women with cervical cancer less than three millimeters in depth.

Bilateral salpingo-oophorectomy: In this procedure, the fallopian tubes and ovaries are removed at the same time as the hysterectomy. If a woman is close to the age of menopause, her doctor may discuss removing her ovaries and fallopian tubes to reduce the chance that the cancer will recur in one of those organs.

Large Cervical Cancer Lesions:
The following surgical procedures may be used for larger cervical cancer lesions (usually up to four to five centimeters in width), but only if the cancer is all within the cervical tissue. If the cancer has spread beyond the cervix, doctors will usually recommend chemotherapy in combination with radiation therapy.

Trachealectomy: This procedure removes the cervix and surrounding tissue but not the uterus. It is used for women who have a larger cancerous area but wish to preserve the ability to have children. The procedure may include removal of lymph nodes. Typically patients considered for this procedure have to have tumors less than two centimeters in size.

Radical hysterectomy: The surgeon removes the cervix, uterus, part of the vagina and the tissues surrounding the cervix called the parametria. At the same time, the surgeon also removes nearby lymph nodes. Depending on a woman's age and the size of the tumor, she may also have a bilateral salpingo-oophorectomy (removal of the ovaries and fallopian tubes).

Radiation Therapy

Radiation therapy is used for cancers that have spread beyond the cervix (stage II, III or IV) or very large lesions (larger than four centimeters). Radiation therapy uses high-energy X-rays or other types of radiation to kill cancer cells or shrink the tumor. Radiation therapy is used instead of surgery in most cases. However, it is sometimes necessary after surgery if it is discovered that the cancer has spread outside the cervix, or to reduce the risk that a cancer will come back after surgery.

There are two types of radiation therapy:

External radiation therapy uses a machine outside the body to send radiation toward the cervical cancer. Internal radiation therapy uses a small amount of radioactive material that is delivered directly to the tumor using implants.

Internal radiation therapy implants are inserted through the vagina into the cervix, where they are placed next to the tumor while the patient is under anesthesia.

Chemotherapy

Chemotherapy uses drugs to stop the growth of cancer cells either by killing the cells or by stopping them from dividing. Chemotherapy can be given by mouth or injected into a vein or muscle. In most cases, it is given to a patient through a vein during an outpatient visit using systemic chemotherapy. The drugs enter the bloodstream and can reach cancer cells throughout the body. Regional chemotherapy is chemotherapy which is placed directly into an organ or a body cavity, such as the abdomen. Almost all cervical cancer patients in good medical condition who are receiving radiation for stage IIA or higher, will be offered chemotherapy in addition to radiation therapy.

Clinical Trials

New treatments are always being tested in clinical trials and some patients with cancer may want to consider participating in one of these research studies. These studies are meant to help improve current cancer treatments or obtain information on new treatments. Talk to your doctor about the clinical trials that may be right for you.